First report of hemosiderotic adenodermatofibroma in Brazil / Primeiro relato de adenodermatofibroma hemossiderótico no Brasil

ABSTRACT Hemosiderotic adenodermatofibroma is a recently recognized lesion, characterized by a dermal nodule with cystic structures of an apocrine gland, surrounded by a dermatofibroma-like stroma with hemosiderotic macrophages. We present the first case report of this entity in Brazil together with representative images, in addition to a review on the subject and discussion about the apocrine origin of this lesion.

RESUMEN El dermatoadenofibroma hemosiderótico es una lesión recientemente descrita, caracterizada por un nódulo dérmico con estructuras quísticas de una glándula apocrina, rodeado por un estroma del tipo dermatofibroma con macrófagos hemosideróticos. Presentamos el primer reporte de caso de esa entidad en Brasil, junto a imágenes representativas, además de una revisión del tema y discusiones acerca del origen apocrina de esa lesión.

RESUMO Adenodermatofibroma hemossiderótico é uma lesão recentemente conhecida, caracterizada por um nódulo dérmico com estruturas císticas de uma glândula apócrina, circundado por um estroma do tipo dermatofibroma com macrófagos hemossideróticos. Apresentamos o primeiro relato de caso dessa entidade no Brasil junto a imagens representativas, além de uma revisão do assunto e discussões sobre a origem apócrina dessa lesão.

Report of two cases of vacuolar interface dermatitis initially suspected as melanoma in situ and review of the literature / Relato de dois casos de dermatite de interface vacuolar, inicialmente diagnosticados como melanoma in situ, e revisão da literatura

ABSTRACT The diagnosis of melanocytic lesions can be challenging and immunohistochemical study is a valuable tool for dermatopathologists. We report two cases initially simulating melanoma in situ, reviewing the histopathological and immunohistochemical findings and the cases published in the literature with similar findings/results. We emphasize the importance of clinicopathological correlation in the evaluation of lesions with interface changes and in the "pseudomelanocytic nests", which may simulate melanoma in situ. We also highlight the importance of using a immunohistochemistry panel in addition to Melan-A, in the study of these lesions.

RESUMO O diagnóstico de lesões melanocíticas pode ser desafiador, e o estudo imuno-histoquímico é uma ferramenta valiosa para os dermatopatologistas. Relatamos dois casos inicialmente diagnosticados como melanoma in situ, avaliando os achados histopatológicos e imuno-histoquímicos e os casos publicados na literatura com resultados semelhantes. Ressaltamos a importância da correlação clinicopatológica na avaliação das lesões com danos na interface e nos "ninhos pseudomelanocíticos", que podem simular melanoma in situ. Destacamos também a importância da utilização de um painel de imuno-histoquímica, além do Melan-A, no estudo dessas lesões.

White fibrous papulosis of the neck: the first South American case.

A 69-year-old woman presented with white papules on her neck. These papules were multiple, white, discrete, asymptomatic, non-follicular, 2 to 3 mm in diameter, and located on both sides of the neck. On histopathological examination, there was a thickened and abnormal organization of collagen bundles in the papillary to mid-dermis and a decrease in the number of elastic fibers. This clinical and histological picture suggested the diagnosis of white fibrous papulosis of the neck. No treatment was given because of the benign nature of the disease. This is the first case report of this condition in South America.

Sycosiform tinea barbae caused by Trichophyton rubrum.

Tinea barbae is an uncommon superficial dermatophyte infection of the beard and moustache areas. It was more frequently observed in the past, before single-use razors became available. In most cases, the zoophilic ectothrix Trichophyton mentagrophytes and Trichophyton verrucosum are responsible for this type of infection. Its clinical presentation is variable; it can mimic many other skin disorders such as sycosis, iododerma, contact dermatitis, perioral dermatitis, and actinomycosis. We report a case of tinea barbae caused by an uncommon agent Trichophyton rubrum, misdiagnosed as sycosis, and review the approach and management of the disease.

Acquired fibrokeratoma presenting as a giant pedunculated lesion on the heel.

Acquired digital fibrokeratomas (ADF) are benign and uncommon lesions consisting of collagenous papules and nodules covered by hyperkeratotic epidermis. These tumors occur mainly on the fingers and toes and infrequently on the palms and soles. They may possibly be triggered by a reaction to a trauma, ADF usually present as small and solitary dome-shaped lesions with a collarete of slightly raised skin at the base. We report a rare case of fibrokeratoma of the heel, presenting as a large and pedunculated nodule.

Edema hemorrágico agudo da infância / Infantile acute hemorrhagic edema

O edema hemorrágico agudo da infância é uma vasculite leucocitoclástica rara que acomete crianças com menos de dois anos de idade. A doença tem curso benigno, geralmente sem complicações ou recidivas. Descreve-se um caso em criança de um ano e cinco meses de idade cujos achados clínicos e histopatológicos são típicos do edema agudo hemorrágico da infância.

Infantile acute hemorrhagic edema is a rare leukocytoclastic vasculitis that affects children under 2 years of age. The disease has a benign outcome usually with no complications or recurrence. We report the case of a 17-month-old girl with clinical and histopathological findings that are typical of infantile acute hemorrhagic edema.

Linfoma com lesäo vertebral em paciente com síndrome da imunodeficiência adquirida: um relato de caso / Lymphoma and vertebral involvement in acquired immunodeficiency syndrome: a case report

Os autores relatam um caso de linfoma linfoblástico em paciente portador da síndrome de imunodeficiência adquirida (SIDA), que se tornou interessante pelo comprometimento medular. Näo foi encontrado na literatura relato prévio de lesäo óssea condicionada por linfoma em paciente com SIDA